Blogs: Unassigned Entry #1: Reaction Mechanism of the Reddy Alcohol to Amine Reaction

The Reddy Alcohol to Amine Reaction is an incredibly useful organic chemistry reaction. In essence, it is a combination of a modified Appel reaction, followed by a Staudinger reaction, all done in one reaction vessel. The basics are as follows:

This reaction actually proceeds through several steps. First, the thriphenylphosphine abstracts a chlorine from the carbon tetrachloride.

Then, the thrichloromethanide abstracts the hydroxy hydrogen from the alcohol. The resulting alkoxy (or aryloxy) displaces the chloride in the PPh₃Cl^- anion.

The azide attacks the R group, a process driven forward by triphenylphosphine oxide's stability. By diluting the carbon tetrachloride with dimethylformamide, the chances of unwanted organochlorine formation is drastically lowered.

The alkyl azide is then attacked by a second triphenylphosphine, generating a phosphazide.The phosphazide attacks itself, creating a cyclic intermediate. This intermediate releases molecular nitrogen and forms an iminophosphorane. Upon work-up with water, the primary amine is formed.

Blogs: Assigned Entry #1: Blogs I Like

Blogs can be a great way to present information to interested parties; people all over the world can read and share in the common body of human knowledge. While Sturgeon's Law guarantees that many, many blogs will leave much to be desired, but the great ones can truly be gems.

There are many of these good blogs out there; Superclassical is a good source of information on the philosophy of logic. I definitely recommend it to any logical positivists out there as well as any staunch logical anti-positivists. I'd give it a 9/10.

Derek Lowe's In the Pipeline is a nice place to read on all the latest pharmaceutical research news, but its combination of highly opinionated and highly technical writing is a bit off-putting. All in all, I'd give it a 7/10

Rationally Speaking is a less than stellar.example. Under the patina of professionalism lies a highly personal and unfounded philosophy based on the importance of individuals. Such subjective and relativistic philosophy requires better support. It gets a 4/10.

Blogs: Assigned Entry #0: Introduction Practice Entry

Greetings, people of Blogger. I am Chris. My passions are organic chemistry and philosophy. In my spare time, I run a philosophy blog on Tumblr, The Thunderer's Empire. I came to Glendale Community College to improve myself, and to eventually transfer to the University of Arizona. I have many hopes for this blog, including:

• Attract new readers to my main blog
• Enhance my blogging skills
• Entertain and inform others
• Foster interest in philosophy or organic chemistry
• Get a good grade in this class

If you have any questions or concerns, you can send me an email at chr2132317@maricopa.edu.